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Codeine is known to interfere with a few medicines. It is especially essential to explain to your medical doctor or pharmacist if you are taking the following medicines:

Elle n'est pas soumise à la sanction pénale mais est citée dans la Convention special sur les stupéfiants de 1961 dans la catégorie des « substances présentant un risque d'abus moindre du fait de leur use médical ».

Antihistamines: concomitant administration of codeine and antihistamines with sedative Attributes may possibly trigger greater CNS despair and/or respiratory despair and/or hypotension.

four.eight Unwanted consequences Standard prolonged use of codeine is thought to bring on dependancy and tolerance. Symptoms of restlessness and irritability might result when treatment is then stopped.

Excipients Codeine Phosphate Tablets contain lactose. Clients with uncommon hereditary complications of galactose intolerance, full lactase deficiency or glucose-galactose malabsorption must not get this drugs.

Administration in the course of labour may depress respiration during the neonate and an antidote for the kid needs to be available.

This medicine can impair cognitive operate and may have an affect on a patient's capability to drive safely. This course of drugs is within the list of prescription drugs A part of regulations under 5a from the Road of Website traffic Act 1988. When prescribing this medicine, sufferers ought to be advised:

Codeine Phosphate Tablets should not be taken by kids under the age of twelve years resulting from the chance of severe breathing issues.

Administration of pethidine And maybe other opioid analgesics to people having a monoamine oxidase inhibitor (MAOI) has actually been connected to pretty severe click here and at times fatal reactions.

Codeine is actually a centrally acting weak analgesic. Codeine exerts its result by way of µ opioid receptors, although codeine has low affinity for these receptors, and its analgesic outcome is due to its conversion to morphine.

Administration for the duration of labour may well depress respiration from the click here neonate and an antidote for the child needs to be available.

Signs or symptoms Central nervous process despair, including respiratory despair, may perhaps build but is unlikely to become extreme Until other sedative brokers have already been co-ingested, which include Liquor, or maybe the overdose is incredibly large. The triad of coma, pinpoint pupils and respiratory melancholy is taken into account indicative of opioid overdosage with dilation of your pupils taking place as hypoxia develops.

Constipation is a standard facet impact of both equally codeine and hydrocodone use and sometimes proceeds in the course of therapy. Persons might acquire stool softeners and raise their fluid ingestion to assist decrease this facet result.

For Moderate to Reasonable Discomfort Codeine should be utilised at the lowest efficient dose with the shortest time period. This dose might be taken, nearly 4 situations every day at intervals of not lower than six hours. Utmost every day dose of codeine should not exceed 240 mg.